Kinesin and dynein are two microtubule-based motor proteins, which play important roles in cellular cargo transportation, cell division and signal transduction. I will present our recent results on theoretical studies of the molecular mechanism of energy usage by these two motor proteins. I will discuss how energy is used efficiently but in different ways by these two motor proteins, which share the same track but "walk" in opposite directions. I will also describe some of our recent effort in developing multi-scale simulation methods and applying these methods to study large scale protein conformational changes.

□　世話人：田中成典 (発達科学部 自然環境論講座)
　　　　　　　　e-mail: tanaka2@kobe-u.ac.jp
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